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Quantitative study of cytotoxic T-lymphocyte immunotherapy for nasopharyngeal carcinoma

Overview of attention for article published in Theoretical Biology and Medical Modelling, March 2012
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Title
Quantitative study of cytotoxic T-lymphocyte immunotherapy for nasopharyngeal carcinoma
Published in
Theoretical Biology and Medical Modelling, March 2012
DOI 10.1186/1742-4682-9-6
Pubmed ID
Authors

Wang Shengjun, Guo Yunbo, Song Liyan, Li Jinming, Deng Qinkai

Abstract

In clinical practice, the common strategy for immunotherapy of nasopharyngeal carcinoma (NPC) is to infuse cytotoxic T-lymphocyte (CTL) lines several times by intravenous injection, but it is difficult by laboratory research to investigate the relationship between treatment time-point, the amount of CTL added and the therapeutic effect. The objective of this study is to establish a mathematical model to study the therapeutic effect of different treatment time-points and amounts of CTL, and to predict the change in therapeutic effect when the percentage of EBV LMP2-specific CTL is increased from 10% to 20%.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 40%
Student > Ph. D. Student 1 20%
Student > Bachelor 1 20%
Professor > Associate Professor 1 20%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 2 40%
Mathematics 1 20%
Nursing and Health Professions 1 20%
Medicine and Dentistry 1 20%