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The predictive role of early activation of natural killer cells in septic shock

Overview of attention for article published in Critical Care, March 2012
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Title
The predictive role of early activation of natural killer cells in septic shock
Published in
Critical Care, March 2012
DOI 10.1186/cc11204
Pubmed ID
Authors

Raúl de Pablo, Jorge Monserrat, Carolina Torrijos, Mercedes Martín, Alfredo Prieto, Melchor Alvarez-Mon

Abstract

Recently, several studies about the role of natural killer (NK) cells in sepsis have been highlighted. In an earlier study, we characterized the abnormalities of circulating lymphocytes in 52 patients with septic shock during the first 28 days in the intensive care unit. Our results confirm and expand some previous reports. We found that patients who did not survive exhibited less NK cell (CD3-CD56⁺) depletion than survivors and that these NK cells expressed CD69⁺ and CD57⁺. These data demonstrate that NK cells are key participants in septic shock because patients who survived have more depletion and expressed less early activation and differentiation.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 9%
Germany 1 4%
France 1 4%
Unknown 19 83%

Demographic breakdown

Readers by professional status Count As %
Other 5 22%
Student > Ph. D. Student 2 9%
Researcher 2 9%
Professor > Associate Professor 2 9%
Student > Master 2 9%
Other 4 17%
Unknown 6 26%
Readers by discipline Count As %
Medicine and Dentistry 12 52%
Biochemistry, Genetics and Molecular Biology 1 4%
Veterinary Science and Veterinary Medicine 1 4%
Immunology and Microbiology 1 4%
Agricultural and Biological Sciences 1 4%
Other 0 0%
Unknown 7 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2012.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from Critical Care
#5,970
of 6,554 outputs
Outputs of similar age
#132,054
of 168,509 outputs
Outputs of similar age from Critical Care
#89
of 123 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one is in the 2nd percentile – i.e., 2% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,509 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 123 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.