Title |
Phylogenetic reconstruction of dengue virus type 2 in Colombia
|
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Published in |
Virology Journal, March 2012
|
DOI | 10.1186/1743-422x-9-64 |
Pubmed ID | |
Authors |
Jairo A Méndez, José A Usme-Ciro, Cristina Domingo, Gloria J Rey, Juan A Sánchez, Antonio Tenorio, Juan C Gallego-Gomez |
Abstract |
Dengue fever is perhaps the most important viral re-emergent disease especially in tropical and sub-tropical countries, affecting about 50 million people around the world yearly. In Colombia, dengue virus was first detected in 1971 and still remains as a major public health issue. Although four viral serotypes have been recurrently identified, dengue virus type 2 (DENV-2) has been involved in the most important outbreaks during the last 20 years, including 2010 when the fatality rate highly increased. As there are no major studies reviewing virus origin and genotype distribution in this country, the present study attempts to reconstruct the phylogenetic history of DENV-2 using a sequence analysis from a 224 bp PCR-amplified product corresponding to the carboxyl terminus of the envelope (E) gene from 48 Colombian isolates. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 3 | 2% |
Brazil | 2 | 2% |
Canada | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 120 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 27 | 21% |
Student > Bachelor | 27 | 21% |
Student > Ph. D. Student | 19 | 15% |
Researcher | 18 | 14% |
Student > Doctoral Student | 7 | 6% |
Other | 19 | 15% |
Unknown | 10 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 50 | 39% |
Medicine and Dentistry | 18 | 14% |
Biochemistry, Genetics and Molecular Biology | 17 | 13% |
Immunology and Microbiology | 9 | 7% |
Social Sciences | 3 | 2% |
Other | 11 | 9% |
Unknown | 19 | 15% |