Title |
Translational Investigation and Treatment of Neuropathic Pain
|
---|---|
Published in |
Molecular Pain, January 2012
|
DOI | 10.1186/1744-8069-8-15 |
Pubmed ID | |
Authors |
Bo Xu, Giannina Descalzi, Hai-Rong Ye, Min Zhuo, Ying-Wei Wang |
Abstract |
Neuropathic pain develops from a lesion or disease affecting the somatosensory system. Translational investigations of neuropathic pain by using different animal models reveal that peripheral sensitization, spinal and cortical plasticity may play critical roles in neuropathic pain. Furthermore, descending facilitatory or excitatory modulation may also act to enhance chronic pain. Current clinical therapy for neuropathic pain includes the use of pharmacological and nonpharmacological (psychological, physical, and surgical treatment) methods. However, there is substantial need to better medicine for treating neuropathic pain. Future translational researchers and clinicians will greatly facilitate the development of novel drugs for treating chronic pain including neuropathic pain. |
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United States | 1 | 17% |
Germany | 1 | 17% |
United Kingdom | 1 | 17% |
Unknown | 2 | 33% |
Demographic breakdown
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Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
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United States | 3 | 2% |
Portugal | 1 | <1% |
Indonesia | 1 | <1% |
Russia | 1 | <1% |
Canada | 1 | <1% |
Spain | 1 | <1% |
Poland | 1 | <1% |
Unknown | 122 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 19 | 15% |
Student > Master | 18 | 14% |
Student > Bachelor | 17 | 13% |
Researcher | 16 | 12% |
Student > Postgraduate | 13 | 10% |
Other | 32 | 24% |
Unknown | 16 | 12% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 39 | 30% |
Agricultural and Biological Sciences | 23 | 18% |
Neuroscience | 15 | 11% |
Psychology | 9 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 9 | 7% |
Other | 19 | 15% |
Unknown | 17 | 13% |