Title |
Optimized labeling of bone marrow mesenchymal cells with superparamagnetic iron oxide nanoparticles and in vivo visualization by magnetic resonance imaging
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Published in |
Journal of Nanobiotechnology, February 2011
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DOI | 10.1186/1477-3155-9-4 |
Pubmed ID | |
Authors |
Jasmin, Ana Luiza M Torres, Henrique MP Nunes, Juliana A Passipieri, Linda A Jelicks, Emerson L Gasparetto, David C Spray, Antonio C Campos de Carvalho, Rosalia Mendez-Otero |
Abstract |
Stem cell therapy has emerged as a promising addition to traditional treatments for a number of diseases. However, harnessing the therapeutic potential of stem cells requires an understanding of their fate in vivo. Non-invasive cell tracking can provide knowledge about mechanisms responsible for functional improvement of host tissue. Superparamagnetic iron oxide nanoparticles (SPIONs) have been used to label and visualize various cell types with magnetic resonance imaging (MRI). In this study we performed experiments designed to investigate the biological properties, including proliferation, viability and differentiation capacity of mesenchymal cells (MSCs) labeled with clinically approved SPIONs. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 3% |
United States | 2 | 3% |
India | 1 | 1% |
Unknown | 65 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 22 | 31% |
Student > Master | 14 | 20% |
Researcher | 8 | 11% |
Student > Doctoral Student | 5 | 7% |
Student > Bachelor | 4 | 6% |
Other | 11 | 16% |
Unknown | 6 | 9% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 19 | 27% |
Medicine and Dentistry | 14 | 20% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Materials Science | 7 | 10% |
Engineering | 4 | 6% |
Other | 7 | 10% |
Unknown | 11 | 16% |