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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Variable use of amiodarone is associated with a greater risk of recurrence of atrial fibrillation in the critically ill
|
|---|---|
| Published in |
Critical Care, April 2016
|
| DOI | 10.1186/s13054-016-1252-2 |
| Pubmed ID | |
| Authors |
Goran Mitrić, Andrew Udy, Hiran Bandeshe, Pierre Clement, Rob Boots |
| Abstract |
Atrial fibrillation is a common rhythm disturbance in the general medical-surgical intensive care unit. Amiodarone is a popular drug in this setting but evidence to inform clinical practice remains scarce. We aimed to identify whether variation in the clinical use of amiodarone was associated with recurrent atrial fibrillation. This was a retrospective audit of 177 critically ill patients who developed new-onset atrial fibrillation after admission to a tertiary level medical-surgical trauma intensive care unit. Patterns of amiodarone prescription (including dosage schedule and duration) were assessed in relation to recurrence of atrial fibrillation during the intensive care unit stay. Known recurrence risk factors, such as inotrope administration, cardiac disease indices, Charlson Comorbidity Index, magnesium concentrations, fluid balance, and potassium concentrations, were also included in adjusted analysis using forward stepwise logistic regression modelling. The cohort had a median (interquartile range) age of 69 years (60-75), Acute Physiology and Chronic Health Evalution II score of 22 (17-28) and Charlson Comorbidity Index of 2 (1-4). A bolus dose of amiodarone followed by infusion (P = 0.02), in addition to continuing amiodarone infusion through to discharge from the intensive care unit (P < 0.001), were associated with less recurrent dysrhythmia. Recurrence after successful treatment was associated with ceasing amiodarone while an inotrope infusion continued (P < 0.001), and was more common in patients with a prior history of congestive cardiac failure (P = 0.04), and a diagnosis of systemic inflammatory response syndrome (P = 0.02). Amiodarone should be administered as a bolus dose followed immediately with an infusion when treating atrial fibrillation in the medical-surgical intensive care unit. Consideration should be given to continuing amiodarone infusions in patients on inotropes until they are ceased. |
X Demographics
The data shown below were collected from the profiles of 50 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 14 | 28% |
| United States | 7 | 14% |
| Malaysia | 2 | 4% |
| Saudi Arabia | 1 | 2% |
| Spain | 1 | 2% |
| Colombia | 1 | 2% |
| Sweden | 1 | 2% |
| Ecuador | 1 | 2% |
| South Africa | 1 | 2% |
| Other | 4 | 8% |
| Unknown | 17 | 34% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 29 | 58% |
| Practitioners (doctors, other healthcare professionals) | 14 | 28% |
| Scientists | 5 | 10% |
| Science communicators (journalists, bloggers, editors) | 2 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 68 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 13 | 19% |
| Student > Postgraduate | 9 | 13% |
| Researcher | 8 | 12% |
| Student > Master | 5 | 7% |
| Student > Ph. D. Student | 4 | 6% |
| Other | 15 | 22% |
| Unknown | 15 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 39 | 57% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 6% |
| Nursing and Health Professions | 3 | 4% |
| Engineering | 2 | 3% |
| Biochemistry, Genetics and Molecular Biology | 1 | 1% |
| Other | 4 | 6% |
| Unknown | 16 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 June 2016.
All research outputs
#1,332,860
of 25,374,647 outputs
Outputs from Critical Care
#1,137
of 6,554 outputs
Outputs of similar age
#22,639
of 314,990 outputs
Outputs of similar age from Critical Care
#33
of 98 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,990 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 98 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.