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β-Glucan exacerbates allergic airway responses to house dust mite allergen

Overview of attention for article published in Respiratory Research, April 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (63rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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2 Facebook pages

Citations

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22 Dimensions

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41 Mendeley
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Title
β-Glucan exacerbates allergic airway responses to house dust mite allergen
Published in
Respiratory Research, April 2016
DOI 10.1186/s12931-016-0352-5
Pubmed ID
Authors

Sabelo Hadebe, Frank Kirstein, Kaat Fierens, Pierre Redelinghuys, Graeme I. Murray, David L. Williams, Bart N. Lambrecht, Frank Brombacher, Gordon D. Brown

Abstract

β-(1,3)-Glucan is present in mould cell walls and frequently detected in house dust mite (HDM) faeces. β-Glucan exposure is thought to be associated with pulmonary allergic inflammation in mouse and man, although the published data are inconsistent. Here, we show that highly purified β-glucan exacerbates HDM-induced eosinophilic, T helper 2 type airway responses by acting as an adjuvant, promoting activation, proliferation and polarisation of HDM-specific T cells (1-Derβ T cells). We therefore provide definitive evidence that β-glucan can influence allergic pulmonary inflammation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 20%
Student > Ph. D. Student 7 17%
Student > Master 6 15%
Student > Bachelor 4 10%
Lecturer 2 5%
Other 3 7%
Unknown 11 27%
Readers by discipline Count As %
Immunology and Microbiology 9 22%
Agricultural and Biological Sciences 7 17%
Medicine and Dentistry 4 10%
Biochemistry, Genetics and Molecular Biology 4 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 3 7%
Unknown 12 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2021.
All research outputs
#8,261,140
of 25,371,288 outputs
Outputs from Respiratory Research
#1,103
of 3,062 outputs
Outputs of similar age
#110,527
of 314,983 outputs
Outputs of similar age from Respiratory Research
#18
of 43 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,983 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.