Title |
Clinical utility of serum biomarkers in Duchenne muscular dystrophy
|
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Published in |
Clinical Proteomics, April 2016
|
DOI | 10.1186/s12014-016-9109-x |
Pubmed ID | |
Authors |
Yetrib Hathout, Haeri Seol, Meng Hsuan J. Han, Aiping Zhang, Kristy J. Brown, Eric P. Hoffman |
Abstract |
Assessments of disease progression and response to therapies in Duchenne muscular dystrophy (DMD) patients remain challenging. Current DMD patient assessments include complex physical tests and invasive procedures such as muscle biopsies, which are not suitable for young children. Defining alternative, less invasive and objective outcome measures to assess disease progression and response to therapy will aid drug development and clinical trials in DMD. In this review we highlight advances in development of non-invasive blood circulating biomarkers as a means to assess disease progression and response to therapies in DMD. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Qatar | 1 | 10% |
United States | 1 | 10% |
Unknown | 8 | 80% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 9 | 90% |
Scientists | 1 | 10% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 122 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 23 | 19% |
Student > Master | 17 | 14% |
Student > Ph. D. Student | 15 | 12% |
Student > Bachelor | 12 | 10% |
Professor > Associate Professor | 5 | 4% |
Other | 20 | 16% |
Unknown | 30 | 25% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 27 | 22% |
Medicine and Dentistry | 20 | 16% |
Agricultural and Biological Sciences | 18 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
Engineering | 4 | 3% |
Other | 14 | 11% |
Unknown | 35 | 29% |