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Severity of liver cirrhosis: a key role in the selection of surgical modality for Child-Pugh A hepatocellular carcinoma

Overview of attention for article published in World Journal of Surgical Oncology, April 2015
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Title
Severity of liver cirrhosis: a key role in the selection of surgical modality for Child-Pugh A hepatocellular carcinoma
Published in
World Journal of Surgical Oncology, April 2015
DOI 10.1186/s12957-015-0567-9
Pubmed ID
Authors

Er-lei Zhang, Bin-yong Liang, Xiao-ping Chen, Zhi-yong Huang

Abstract

Hepatocellular carcinoma is the third leading cause of cancer-related death in the world, and cirrhosis is the main cause of hepatocellular carcinoma and adversely affects surgical outcomes. Liver resection, liver transplantation, and local ablation are potentially curative therapies for early hepatocellular carcinoma (HCC). There exists an obvious histological variability of severity within cirrhosis which has different clinical stages. For patients with Child-Pugh B cirrhosis and/or portal hypertension and HCC within Milan criteria, consensus guidelines suggest that liver transplantation is the best treatment of choice; liver resection is widely accepted as first-line treatment for patients with early-stage HCC and preserved liver function; and local ablation is the treatment of choice in patients with small tumors who are not candidates for surgery or can be used as a temporary treatment during the waiting period for transplantation. For patients with compensated cirrhosis or Child A cirrhosis, the selection of surgical modality based on subclassification of cirrhosis remains unclear. This review examines the current status of the selection of surgical modality for hepatocellular carcinoma treatment in cirrhotic patients and aims to emphasize the effects of the severity of cirrhosis on the selection of surgical modality for the treatment of hepatocellular carcinoma.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Germany 1 4%
Unknown 22 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 21%
Student > Postgraduate 4 17%
Student > Master 4 17%
Other 2 8%
Student > Bachelor 2 8%
Other 5 21%
Unknown 2 8%
Readers by discipline Count As %
Medicine and Dentistry 13 54%
Agricultural and Biological Sciences 3 13%
Nursing and Health Professions 2 8%
Biochemistry, Genetics and Molecular Biology 1 4%
Economics, Econometrics and Finance 1 4%
Other 1 4%
Unknown 3 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2016.
All research outputs
#20,318,358
of 22,860,626 outputs
Outputs from World Journal of Surgical Oncology
#1,582
of 2,045 outputs
Outputs of similar age
#223,135
of 264,030 outputs
Outputs of similar age from World Journal of Surgical Oncology
#52
of 63 outputs
Altmetric has tracked 22,860,626 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,045 research outputs from this source. They receive a mean Attention Score of 2.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.