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Clinicopathologic features of ovarian neoplasms with emphasis on borderline ovarian tumors: an institutional perspective

Overview of attention for article published in BMC Research Notes, April 2016
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Title
Clinicopathologic features of ovarian neoplasms with emphasis on borderline ovarian tumors: an institutional perspective
Published in
BMC Research Notes, April 2016
DOI 10.1186/s13104-016-2015-5
Pubmed ID
Authors

Atif Ali Hashmi, Zubaida Fida Hussain, Aneel Roy Bhagwani, Muhammad Muzzammil Edhi, Naveen Faridi, Syed Danish Hussain, Mehmood Khan

Abstract

Ovarian cancer is the most lethal gynecologic malignancy and it represents third most common malignancy in Karachi (after breast and oral cancer). Due to lack of well established cancer registry in our country, changing trends of ovarian tumors has not been determined. Therefore we aimed to establish the current trends and classification of ovarian tumors in our setup according to latest WHO guidelines. We retrospectively analyzed 162 cases of ovarian tumors that underwent surgical resection from January 2009 till December 2014. Specimens were received in histopathology department, Liaquat National hospital and cases were examined by senior histopathologists and classified according to latest WHO guidelines. Various histopathologic parameters including capsular invasion, omental and lymph node meatstasis along with uterine and fallopian tube involvement were determined apart from tumor type and grade. Mean age at diagnosis was 35.8 years (± 15.5). surface epithelial tumors were most common, 109 cases (67.2 %) followed by germ cell tumors, 44 cases (27.1 %) and sex cord stromal tumors, 8 cases (4.9 %). Serous tumors were most common surface epithelial tumors with 90 % benign morphology. On the other hand, mucinous tumors showed a higher percentage of borderline and malignant features (16.7 and 14.6 % respectively). Higher incidence of capsular invasion and omental metastasis was noted in endometroid and serous carcinoma compared to mucinous tumors. We noted a higher frequency of young age ovarian cancers in our set up. Serous and endometroid carcinomas were found to be associated with adverse prognostic factors like capsular invasion and omental metastasis. Moreover a significantly higher proportion of ovarian tumors constitute mucinous histology including borderline tumors. Whether this represents a changing trend towards biology of these tumors in this part of the world needs to be uncovered by further studies.

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Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 8 24%
Student > Master 6 18%
Student > Doctoral Student 3 9%
Other 2 6%
Student > Bachelor 1 3%
Other 4 12%
Unknown 9 27%
Readers by discipline Count As %
Medicine and Dentistry 14 42%
Biochemistry, Genetics and Molecular Biology 3 9%
Immunology and Microbiology 2 6%
Business, Management and Accounting 1 3%
Nursing and Health Professions 1 3%
Other 2 6%
Unknown 10 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2016.
All research outputs
#20,318,358
of 22,860,626 outputs
Outputs from BMC Research Notes
#3,562
of 4,267 outputs
Outputs of similar age
#255,122
of 301,058 outputs
Outputs of similar age from BMC Research Notes
#86
of 98 outputs
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