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The dual roles of cytokines in Alzheimer’s disease: update on interleukins, TNF-α, TGF-β and IFN-γ

Overview of attention for article published in Translational Neurodegeneration, April 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)

Mentioned by

news
1 news outlet
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2 X users

Readers on

mendeley
380 Mendeley
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Title
The dual roles of cytokines in Alzheimer’s disease: update on interleukins, TNF-α, TGF-β and IFN-γ
Published in
Translational Neurodegeneration, April 2016
DOI 10.1186/s40035-016-0054-4
Pubmed ID
Authors

Cong Zheng, Xin-Wen Zhou, Jian-Zhi Wang

Abstract

Alzheimer's disease (AD) is one of the most common neurodegenerative disorders in the elderly. Although the mechanisms underlying AD neurodegeneration are not fully understood, it is well recognized that inflammation plays a crucial role in the initiation and/or deterioration of AD neurodegeneration. Increasing evidence suggests that different cytokines, including interleukins, TNF-α, TGF-β and IFN-γ, are actively participated in AD pathogenesis and may serve as diagnostic or therapeutic targets for AD neurodegeneration. Here, we review the progress in understanding the important role that these cytokines or neuroinflammation has played in AD etiology and pathogenesis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 380 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Portugal 1 <1%
Unknown 378 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 70 18%
Student > Bachelor 60 16%
Student > Master 59 16%
Researcher 32 8%
Student > Doctoral Student 19 5%
Other 50 13%
Unknown 90 24%
Readers by discipline Count As %
Neuroscience 67 18%
Biochemistry, Genetics and Molecular Biology 53 14%
Agricultural and Biological Sciences 46 12%
Medicine and Dentistry 35 9%
Pharmacology, Toxicology and Pharmaceutical Science 21 6%
Other 51 13%
Unknown 107 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 April 2016.
All research outputs
#3,621,629
of 25,373,627 outputs
Outputs from Translational Neurodegeneration
#191
of 384 outputs
Outputs of similar age
#56,224
of 315,549 outputs
Outputs of similar age from Translational Neurodegeneration
#3
of 4 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 384 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.7. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,549 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.