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FE65 as a link between VLDLR and APP to regulate their trafficking and processing

Overview of attention for article published in Molecular Neurodegeneration, March 2012
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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Title
FE65 as a link between VLDLR and APP to regulate their trafficking and processing
Published in
Molecular Neurodegeneration, March 2012
DOI 10.1186/1750-1326-7-9
Pubmed ID
Authors

Sonya B Dumanis, Kelly A Chamberlain, Yoo Jin Sohn, Young Jin Lee, Suzanne Y Guénette, Toshiharu Suzuki, Paul M Mathews, Daniel TS Pak, G William Rebeck, Yoo-hun Suh, Hee-Sae Park, Hyang-Sook Hoe

Abstract

Several studies found that FE65, a cytoplasmic adaptor protein, interacts with APP and LRP1, altering the trafficking and processing of APP. We have previously shown that FE65 interacts with the ApoE receptor, ApoER2, altering its trafficking and processing. Interestingly, it has been shown that FE65 can act as a linker between APP and LRP1 or ApoER2. In the present study, we tested whether FE65 can interact with another ApoE receptor, VLDLR, thereby altering its trafficking and processing, and whether FE65 can serve as a linker between APP and VLDLR.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Spain 1 2%
Unknown 55 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 19%
Student > Master 10 17%
Student > Doctoral Student 8 14%
Researcher 8 14%
Student > Bachelor 5 9%
Other 8 14%
Unknown 8 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 43%
Neuroscience 7 12%
Biochemistry, Genetics and Molecular Biology 5 9%
Medicine and Dentistry 5 9%
Immunology and Microbiology 2 3%
Other 5 9%
Unknown 9 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 August 2012.
All research outputs
#15,242,707
of 22,663,969 outputs
Outputs from Molecular Neurodegeneration
#712
of 842 outputs
Outputs of similar age
#101,868
of 159,669 outputs
Outputs of similar age from Molecular Neurodegeneration
#6
of 15 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 842 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.0. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 159,669 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.