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Intravitreal treatment in patients with exudative age-related macular degeneration and visual acuity ≤ 0.05

Overview of attention for article published in BMC Ophthalmology, October 2015
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Title
Intravitreal treatment in patients with exudative age-related macular degeneration and visual acuity ≤ 0.05
Published in
BMC Ophthalmology, October 2015
DOI 10.1186/s12886-015-0123-y
Pubmed ID
Authors

Raphael Koch, Matthias Schmidt, Sabine Gebauer, Holger Busse, Constantin E. Uhlig

Abstract

To investigate intravitreal treatment efficiencies in patients suffering from exudative ARMD with a BCVA ≤ 0.05. Retrospective analysis: Analysis parameters were lesion type, BCVA at baseline and at follow-up, the intravitreal drug used, and its application frequency. Patients were divided into: 1) following injections of bevacizumab, triamcinolone, their combination, or ranibizumab regardless of their lesion subtype, 2) or by lesion subtype. Statistical tests were performed using Wilcoxon signed-rank tests, Kruskal-Wallis tests and multivariable logistic regressions. Seventy four eyes of 74 patients were analyzed. Follow-up was at 12.0 to 15.7 weeks. Median difference of BCVA (logMAR) between baseline and follow-up was 0.000 (-0.030, 0.175) in classic (p = 0.105), 0.000 (-1.15, 0.20) in occult (p = 0.005), -0.200 (-1.20, 0.60) in cases with subretinal fluid (p = 0.207), 0.000 (-0.60, 0.30) in pigment epithelial detachment (p = 0.813), and 0.050 (-0.40, 0.70) in Junius Kuhnt maculopathy (p = 0.344). BCVA increased ≥ 0.2 logMAR in 4 (24 %) classic, 9 (47 %) occult, 6 (33 %) pigment epithelial detachment, 6 (55 %) subretinal fluid, in 29 (39 %) eyes regardless of the lesion type, and reached a BCVA ≥ 0.05 in 7 (9 %) of those with a baseline BCVA <0.05. Results indicate that in patients with ARMD and a BCVA lower 0.05, intravitreal treatment may improve visual acuity, most probably in cases with occult lesions.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 24%
Student > Master 2 12%
Lecturer > Senior Lecturer 1 6%
Student > Doctoral Student 1 6%
Other 1 6%
Other 2 12%
Unknown 6 35%
Readers by discipline Count As %
Medicine and Dentistry 6 35%
Nursing and Health Professions 3 18%
Agricultural and Biological Sciences 2 12%
Computer Science 1 6%
Unknown 5 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2016.
All research outputs
#20,318,358
of 22,860,626 outputs
Outputs from BMC Ophthalmology
#2,091
of 2,354 outputs
Outputs of similar age
#237,544
of 283,303 outputs
Outputs of similar age from BMC Ophthalmology
#17
of 27 outputs
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We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.