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Mendeley readers
| Title |
A phase II multi-institutional study assessing simultaneous in-field boost helical tomotherapy for 1-3 brain metastases
|
|---|---|
| Published in |
Radiation Oncology, March 2012
|
| DOI | 10.1186/1748-717x-7-42 |
| Pubmed ID | |
| Authors |
George Rodrigues, Slav Yartsev, Keng Yeow Tay, Gregory R Pond, Frank Lagerwaard, Glenn Bauman |
| Abstract |
Our research group has previously published a dosimetric planning study that demonstrated that a 60 Gy/10 fractions intralesional boost with whole-brain radiotherapy (WBRT) to 30 Gy/10 fractions was biologically equivalent with a stereotactic radiosurgery (SRS) boost of 18 Gy/1 fraction with 30 Gy/10 fractions WBRT. Helical tomotherapy (HT) was found to be dosimetrically equivalent to SRS in terms of target coverage and superior to SRS in terms of normal tissue tolerance. A phase I trial has been now completed at our institution with a total of 60 enrolled patients and 48 evaluable patients. The phase II dose has been determined to be the final phase I cohort dose of 60 Gy/10 fractions. |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Philippines | 1 | 2% |
| Unknown | 50 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 12 | 24% |
| Researcher | 8 | 16% |
| Other | 5 | 10% |
| Student > Postgraduate | 4 | 8% |
| Student > Ph. D. Student | 3 | 6% |
| Other | 7 | 14% |
| Unknown | 12 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 45% |
| Nursing and Health Professions | 3 | 6% |
| Physics and Astronomy | 3 | 6% |
| Psychology | 2 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
| Other | 4 | 8% |
| Unknown | 14 | 27% |