Title |
Effects of Corni fructus on ovalbumin-induced airway inflammation and airway hyper-responsiveness in a mouse model of allergic asthma
|
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Published in |
Journal of Inflammation, March 2012
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DOI | 10.1186/1476-9255-9-9 |
Pubmed ID | |
Authors |
Seung-Hyung Kim, Bok-Kyu Kim, Young-Cheol Lee |
Abstract |
Allergic asthma is a chronic inflammatory lung disease that is characterized by airway hyperresponsiveness (AHR) to allergens, airway oedema, increased mucus secretion, excess production of T helper-2 (Th2) cytokines, and eosinophil accumulation in the lungs. Corni fructus (CF) is a fruit of Cornus officinalis Sieb. Et. Zucc. (Cornaceae) and has been used in traditional Korean medicine as an anti-inflammatory, analgesic, and diuretic agent. To investigate the anti-asthmatic effects of CF and their underlying mechanism, we examined the influence of CF on the development of pulmonary eosinophilic inflammation and airway hyperresponsiveness in a mouse model of allergic asthma. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Korea, Republic of | 1 | 5% |
India | 1 | 5% |
Unknown | 19 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 29% |
Student > Master | 5 | 24% |
Student > Bachelor | 2 | 10% |
Professor | 1 | 5% |
Student > Doctoral Student | 1 | 5% |
Other | 1 | 5% |
Unknown | 5 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 14% |
Immunology and Microbiology | 3 | 14% |
Chemistry | 3 | 14% |
Biochemistry, Genetics and Molecular Biology | 2 | 10% |
Medicine and Dentistry | 2 | 10% |
Other | 1 | 5% |
Unknown | 7 | 33% |