Title |
Serum protein profiles as potential biomarkers for infectious disease status in pigs
|
---|---|
Published in |
BMC Veterinary Research, March 2012
|
DOI | 10.1186/1746-6148-8-32 |
Pubmed ID | |
Authors |
Miriam GJ Koene, Han A Mulder, Norbert Stockhofe-Zurwieden, Leo Kruijt, Mari A Smits |
Abstract |
In veterinary medicine and animal husbandry, there is a need for tools allowing the early warning of diseases. Preferably, tests should be available that warn farmers and veterinarians during the incubation periods of disease and before the onset of clinical signs. The objective of this study was to explore the potential of serum protein profiles as an early biomarker for infectious disease status. Serum samples were obtained from an experimental pig model for porcine circovirus-associated disease (PCVAD), consisting of Porcine Circovirus type 2 (PCV2) infection in combination with either Porcine Parvovirus (PPV) or Porcine Reproductive and Respiratory Syndrome virus (PRRSV). Sera were collected before and after onset of clinical signs at day 0, 5 and 19 post infection. Serum protein profiles were evaluated against sera from non-infected control animals. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Denmark | 2 | 4% |
Brazil | 1 | 2% |
Switzerland | 1 | 2% |
Spain | 1 | 2% |
United States | 1 | 2% |
Unknown | 39 | 87% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 13 | 29% |
Student > Ph. D. Student | 7 | 16% |
Student > Master | 4 | 9% |
Other | 4 | 9% |
Student > Doctoral Student | 3 | 7% |
Other | 8 | 18% |
Unknown | 6 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 21 | 47% |
Veterinary Science and Veterinary Medicine | 6 | 13% |
Medicine and Dentistry | 4 | 9% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Business, Management and Accounting | 1 | 2% |
Other | 5 | 11% |
Unknown | 6 | 13% |