@UK_Centrist Apparently, challenge studies with influenza have demonstrated that initial inoculum size *does* influence severity of symptoms. In a race between the immune system and the virus, the greater the initial exposure, the greater the virus' head
RT @geostylegeo: @BelindaMcKeigh1 @AlyssaGoodwitch Ohhhh Belinda... now you've asked the big question that's too big for a tweet! Here is…
@BelindaMcKeigh1 @AlyssaGoodwitch Ohhhh Belinda... now you've asked the big question that's too big for a tweet! Here is an actual article on just that: https://t.co/oU591pgWIB
@ali_meikle Thanks Ali! no clear explanation for that in our data, but maybe related to tendency for innate immune activation? @thefluzee and I speculated along these lines in flu https://t.co/o8G5dPmPnn