Title |
Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts
|
---|---|
Published in |
Radiation Oncology, March 2012
|
DOI | 10.1186/1748-717x-7-41 |
Pubmed ID | |
Authors |
Stefan Rieken, Daniel Habermehl, Thomas Haberer, Oliver Jaekel, Jürgen Debus, Stephanie E Combs |
Abstract |
Particle irradiation was established at the University of Heidelberg 2 years ago. To date, more than 400 patients have been treated including patients with primary brain tumors. In malignant glioma (WHO IV) patients, two clinical trials have been set up-one investigating the benefit of a carbon ion (18 GyE) vs. a proton boost (10 GyE) in addition to photon radiotherapy (50 Gy), the other one investigating reirradiation with escalating total dose schedules starting at 30 GyE. In atypical meningioma patients (WHO °II), a carbon ion boost of 18 GyE is applied to macroscopic tumor residues following previous photon irradiation with 50 Gy.This study was set up in order to investigate toxicity and response after proton and carbon ion therapy for gliomas and meningiomas. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | 2% |
Japan | 1 | <1% |
Denmark | 1 | <1% |
France | 1 | <1% |
Unknown | 100 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 21 | 20% |
Student > Ph. D. Student | 11 | 10% |
Student > Doctoral Student | 10 | 10% |
Student > Bachelor | 10 | 10% |
Researcher | 9 | 9% |
Other | 18 | 17% |
Unknown | 26 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 38% |
Physics and Astronomy | 13 | 12% |
Agricultural and Biological Sciences | 7 | 7% |
Nursing and Health Professions | 3 | 3% |
Neuroscience | 3 | 3% |
Other | 13 | 12% |
Unknown | 26 | 25% |