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Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts

Overview of attention for article published in Radiation Oncology, March 2012
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Title
Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts
Published in
Radiation Oncology, March 2012
DOI 10.1186/1748-717x-7-41
Pubmed ID
Authors

Stefan Rieken, Daniel Habermehl, Thomas Haberer, Oliver Jaekel, Jürgen Debus, Stephanie E Combs

Abstract

Particle irradiation was established at the University of Heidelberg 2 years ago. To date, more than 400 patients have been treated including patients with primary brain tumors. In malignant glioma (WHO IV) patients, two clinical trials have been set up-one investigating the benefit of a carbon ion (18 GyE) vs. a proton boost (10 GyE) in addition to photon radiotherapy (50 Gy), the other one investigating reirradiation with escalating total dose schedules starting at 30 GyE. In atypical meningioma patients (WHO °II), a carbon ion boost of 18 GyE is applied to macroscopic tumor residues following previous photon irradiation with 50 Gy.This study was set up in order to investigate toxicity and response after proton and carbon ion therapy for gliomas and meningiomas.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 2%
Japan 1 <1%
Denmark 1 <1%
France 1 <1%
Unknown 100 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 21 20%
Student > Ph. D. Student 11 10%
Student > Doctoral Student 10 10%
Student > Bachelor 10 10%
Researcher 9 9%
Other 18 17%
Unknown 26 25%
Readers by discipline Count As %
Medicine and Dentistry 40 38%
Physics and Astronomy 13 12%
Agricultural and Biological Sciences 7 7%
Nursing and Health Professions 3 3%
Neuroscience 3 3%
Other 13 12%
Unknown 26 25%