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Mendeley readers
Attention Score in Context
| Title |
A designer hyper interleukin 11 (H11) is a biologically active cytokine
|
|---|---|
| Published in |
BMC Biotechnology, March 2012
|
| DOI | 10.1186/1472-6750-12-8 |
| Pubmed ID | |
| Authors |
Hanna Dams-Kozlowska, Katarzyna Gryska, Eliza Kwiatkowska-Borowczyk, Dariusz Izycki, Stefan Rose-John, Andrzej Mackiewicz |
| Abstract |
Interleukin 11 (IL-11) is a pleiotropic cytokine with anti-apoptotic, anti-inflammatory and hematopoietic potential. The IL-11 activity is determined by the expression of the IL-11R receptor alpha (IL-11Rα) and the signal transducing subunit β (gp130) on the cell membrane. A recombinant soluble form of the IL-11Rα (sIL-11Rα) in combination with IL-11 acts as an agonist on cells expressing the gp130 molecule. We constructed a designer cytokine Hyper IL-11 (H11), which is exclusively composed of naturally existing components. It contains the full length sIL-11Rα connected with the mature IL-11 protein using their natural sequences only. Such a construct has two major advantages: (i) its components are as close as possible to the natural forms of both proteins and (ii) it lacks an artificial linker what should avoid induction of antibody production. |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 3% |
| Unknown | 30 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 19% |
| Student > Master | 6 | 19% |
| Student > Bachelor | 4 | 13% |
| Professor | 2 | 6% |
| Student > Ph. D. Student | 2 | 6% |
| Other | 6 | 19% |
| Unknown | 5 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 8 | 26% |
| Biochemistry, Genetics and Molecular Biology | 8 | 26% |
| Medicine and Dentistry | 4 | 13% |
| Immunology and Microbiology | 2 | 6% |
| Psychology | 1 | 3% |
| Other | 3 | 10% |
| Unknown | 5 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2020.
All research outputs
#7,413,245
of 22,663,969 outputs
Outputs from BMC Biotechnology
#426
of 935 outputs
Outputs of similar age
#52,618
of 160,638 outputs
Outputs of similar age from BMC Biotechnology
#10
of 13 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 935 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 160,638 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.