Title |
Dosimetric and motion analysis of margin-intensive therapy by stereotactic ablative radiotherapy for resectable pancreatic cancer
|
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Published in |
Radiation Oncology, October 2011
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DOI | 10.1186/1748-717x-6-146 |
Pubmed ID | |
Authors |
John H Heinzerling, Ross Bland, John C Mansour, Roderich E Schwarz, Ezequiel Ramirez, Chuxiong Ding, Ramzi Abdulrahman, Thomas P Boike, Timothy Solberg, Robert D Timmerman, Jeffrey J Meyer |
Abstract |
The retroperitoneal margin is a common site of positive surgical margins in patients with resectable pancreatic cancer. Preoperative margin-intensive therapy (MIT) involves delivery of a single high dose of ablative radiotherapy (30 Gy) focused on this surgically inaccessible margin, utilizing stereotactic techniques in an effort to reduce local failure following surgery. In this study, we investigated the motion of regional organs at risk (OAR) utilizing 4DCT, evaluated the dosimetric effects of abdominal compression (AC) to reduce regional motion, and compared various planning techniques to optimize MIT. |
Mendeley readers
Geographical breakdown
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Demographic breakdown
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