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Dosimetric and motion analysis of margin-intensive therapy by stereotactic ablative radiotherapy for resectable pancreatic cancer

Overview of attention for article published in Radiation Oncology, October 2011
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Title
Dosimetric and motion analysis of margin-intensive therapy by stereotactic ablative radiotherapy for resectable pancreatic cancer
Published in
Radiation Oncology, October 2011
DOI 10.1186/1748-717x-6-146
Pubmed ID
Authors

John H Heinzerling, Ross Bland, John C Mansour, Roderich E Schwarz, Ezequiel Ramirez, Chuxiong Ding, Ramzi Abdulrahman, Thomas P Boike, Timothy Solberg, Robert D Timmerman, Jeffrey J Meyer

Abstract

The retroperitoneal margin is a common site of positive surgical margins in patients with resectable pancreatic cancer. Preoperative margin-intensive therapy (MIT) involves delivery of a single high dose of ablative radiotherapy (30 Gy) focused on this surgically inaccessible margin, utilizing stereotactic techniques in an effort to reduce local failure following surgery. In this study, we investigated the motion of regional organs at risk (OAR) utilizing 4DCT, evaluated the dosimetric effects of abdominal compression (AC) to reduce regional motion, and compared various planning techniques to optimize MIT.

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Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 43 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 16%
Student > Ph. D. Student 7 16%
Researcher 5 11%
Student > Bachelor 4 9%
Professor 4 9%
Other 9 20%
Unknown 8 18%
Readers by discipline Count As %
Medicine and Dentistry 22 50%
Physics and Astronomy 5 11%
Engineering 2 5%
Biochemistry, Genetics and Molecular Biology 1 2%
Psychology 1 2%
Other 3 7%
Unknown 10 23%