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miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10

Overview of attention for article published in BMC Cancer, March 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

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8 X users

Citations

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103 Dimensions

Readers on

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67 Mendeley
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Title
miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10
Published in
BMC Cancer, March 2012
DOI 10.1186/1471-2407-12-111
Pubmed ID
Authors

Yating Chen, Jin Zhang, Huijun Wang, Jiayi Zhao, Cheng Xu, Yingying Du, Xin Luo, Fengyun Zheng, Rui Liu, Hongwei Zhang, Duan Ma

Abstract

miRNAs are a group of small RNA molecules regulating target genes by inducing mRNA degradation or translational repression. Aberrant expression of miRNAs correlates with various cancers. Although miR-135a has been implicated in several other cancers, its role in breast cancer is unknown. HOXA10 however, is associated with multiple cancer types and was recently shown to induce p53 expression in breast cancer cells and reduce their invasive ability. Because HOXA10 is a confirmed miR-135a target in more than one tissue, we examined miR-135a levels in relation to breast cancer phenotypes to determine if miR-135a plays role in this cancer type.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
United States 1 1%
Unknown 65 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 24%
Researcher 11 16%
Student > Ph. D. Student 10 15%
Student > Doctoral Student 7 10%
Lecturer 5 7%
Other 10 15%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 30%
Biochemistry, Genetics and Molecular Biology 17 25%
Medicine and Dentistry 13 19%
Neuroscience 2 3%
Immunology and Microbiology 2 3%
Other 4 6%
Unknown 9 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2012.
All research outputs
#3,759,737
of 22,663,969 outputs
Outputs from BMC Cancer
#888
of 8,242 outputs
Outputs of similar age
#24,830
of 160,528 outputs
Outputs of similar age from BMC Cancer
#7
of 60 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,242 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 160,528 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.