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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Extracellular vesicles derived from mesenchymal stromal cells: a therapeutic option in respiratory diseases?
|
|---|---|
| Published in |
Stem Cell Research & Therapy, April 2016
|
| DOI | 10.1186/s13287-016-0317-0 |
| Pubmed ID | |
| Authors |
Soraia C. Abreu, Daniel J. Weiss, Patricia R. M. Rocco |
| Abstract |
Extracellular vesicles (EVs) are plasma membrane-bound fragments released from several cell types, including mesenchymal stromal cells (MSCs), constitutively or under stimulation. EVs derived from MSCs and other cell types transfer molecules (such as DNA, proteins/peptides, mRNA, microRNA, and lipids) and/or organelles with reparative and anti-inflammatory properties to recipient cells. The paracrine anti-inflammatory effects promoted by MSC-derived EVs have attracted significant interest in the regenerative medicine field, including for potential use in lung injuries. In the present review, we describe the characteristics, biological activities, and mechanisms of action of MSC-derived EVs. We also review the therapeutic potential of EVs as reported in relevant preclinical models of acute and chronic respiratory diseases, such as pneumonia, acute respiratory distress syndrome, asthma, and pulmonary arterial hypertension. Finally, we discuss possible approaches for potentiating the therapeutic effects of MSC-derived EVs so as to enable use of this therapy in clinical practice. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 33% |
| Saudi Arabia | 1 | 17% |
| United States | 1 | 17% |
| Unknown | 2 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 174 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 172 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 28 | 16% |
| Researcher | 27 | 16% |
| Student > Ph. D. Student | 25 | 14% |
| Student > Bachelor | 19 | 11% |
| Student > Doctoral Student | 11 | 6% |
| Other | 29 | 17% |
| Unknown | 35 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 43 | 25% |
| Medicine and Dentistry | 36 | 21% |
| Agricultural and Biological Sciences | 21 | 12% |
| Immunology and Microbiology | 6 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 3% |
| Other | 16 | 9% |
| Unknown | 46 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2023.
All research outputs
#5,100,526
of 25,013,816 outputs
Outputs from Stem Cell Research & Therapy
#536
of 2,714 outputs
Outputs of similar age
#74,247
of 306,617 outputs
Outputs of similar age from Stem Cell Research & Therapy
#13
of 34 outputs
Altmetric has tracked 25,013,816 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,714 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,617 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.