@BiotechMongoose @dkjhaunc We've been pretty loose with our nomenclature, for sure. What we typically call essential genes in mammalian KO screens are those that cause a sufficient fitness defect that they'd be rapidly outcompeted by WT cells. E.g. Fig 1 h
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Latest from the Moffat lab: #BAGEL- fast & accurate tool for finding essential genes from pooled library screens https://t.co/B98YbSqBTg
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BAGEL: a computational framework for identifying essential genes from pooled library screens https://t.co/F5tOkWGCVa #bmcbioinformatics
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BAGEL: a computational framework for identifying essential genes from pooled library screens: The adaptation o... https://t.co/fAHqjAbwvC