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Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients

Overview of attention for article published in Journal of Neuroinflammation, January 2010
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4 X users
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1 Facebook page

Citations

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103 Dimensions

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147 Mendeley
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Title
Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients
Published in
Journal of Neuroinflammation, January 2010
DOI 10.1186/1742-2094-7-5
Pubmed ID
Authors

Shawn G Rhind, Naomi T Crnko, Andrew J Baker, Laurie J Morrison, Pang N Shek, Sandro Scarpelini, Sandro B Rizoli

Abstract

Traumatic brain injury (TBI) initiates interrelated inflammatory and coagulation cascades characterized by wide-spread cellular activation, induction of leukocyte and endothelial cell adhesion molecules and release of soluble pro/antiinflammatory cytokines and thrombotic mediators. Resuscitative care is focused on optimizing cerebral perfusion and reducing secondary injury processes. Hypertonic saline is an effective osmotherapeutic agent for the treatment of intracranial hypertension and has immunomodulatory properties that may confer neuroprotection. This study examined the impact of hypertonic fluids on inflammatory/coagulation cascades in isolated head injury.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 147 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Portugal 1 <1%
Canada 1 <1%
Unknown 143 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 20 14%
Student > Bachelor 17 12%
Other 13 9%
Researcher 13 9%
Student > Doctoral Student 13 9%
Other 46 31%
Unknown 25 17%
Readers by discipline Count As %
Medicine and Dentistry 66 45%
Nursing and Health Professions 12 8%
Neuroscience 12 8%
Agricultural and Biological Sciences 10 7%
Psychology 5 3%
Other 13 9%
Unknown 29 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 May 2013.
All research outputs
#14,915,476
of 25,374,917 outputs
Outputs from Journal of Neuroinflammation
#1,634
of 2,951 outputs
Outputs of similar age
#138,815
of 173,136 outputs
Outputs of similar age from Journal of Neuroinflammation
#8
of 12 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,951 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 173,136 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.