Title |
Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci
|
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Published in |
Molecular Autism, April 2012
|
DOI | 10.1186/2040-2392-3-2 |
Pubmed ID | |
Authors |
Dale J Hedges, Kara L Hamilton-Nelson, Stephanie J Sacharow, Laura Nations, Gary W Beecham, Zhanna M Kozhekbaeva, Brittany L Butler, Holly N Cukier, Patrice L Whitehead, Deqiong Ma, James M Jaworski, Lubov Nathanson, Joycelyn M Lee, Stephen L Hauser, Jorge R Oksenberg, Michael L Cuccaro, Jonathan L Haines, John R Gilbert, Margaret A Pericak-Vance |
Abstract |
Autism spectrum disorders (ASD) represent a group of neurodevelopmental disorders characterized by a core set of social-communicative and behavioral impairments. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain, acting primarily via the GABA receptors (GABR). Multiple lines of evidence, including altered GABA and GABA receptor expression in autistic patients, indicate that the GABAergic system may be involved in the etiology of autism. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 14% |
Mexico | 1 | 14% |
Spain | 1 | 14% |
United Kingdom | 1 | 14% |
Ireland | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 57% |
Scientists | 2 | 29% |
Science communicators (journalists, bloggers, editors) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Iceland | 1 | <1% |
Portugal | 1 | <1% |
Germany | 1 | <1% |
Unknown | 121 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 21 | 17% |
Student > Master | 19 | 15% |
Student > Ph. D. Student | 12 | 10% |
Student > Doctoral Student | 12 | 10% |
Student > Bachelor | 10 | 8% |
Other | 25 | 20% |
Unknown | 27 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 22 | 17% |
Psychology | 18 | 14% |
Biochemistry, Genetics and Molecular Biology | 17 | 13% |
Medicine and Dentistry | 12 | 10% |
Neuroscience | 8 | 6% |
Other | 19 | 15% |
Unknown | 30 | 24% |