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Point-of-care capillary HbA1c measurement in the emergency department: a useful tool to detect unrecognized and uncontrolled diabetes

Overview of attention for article published in International Journal of Emergency Medicine, February 2016
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Title
Point-of-care capillary HbA1c measurement in the emergency department: a useful tool to detect unrecognized and uncontrolled diabetes
Published in
International Journal of Emergency Medicine, February 2016
DOI 10.1186/s12245-016-0107-6
Pubmed ID
Authors

Fernando Gomez-Peralta, Cristina Abreu, Leonor Andreu-Urioste, Ana Cristina Antolí, Carmen Rico-Fontsaré, David Martín-Fernández, Rosa Resina-Rufes, Juan Jesús Pérez-García, Ángela Negrete-Muñoz, Daniel Muñoz-Álvarez, Guillermo E. Umpierrez

Abstract

Inpatient hyperglycaemia and diabetes mellitus (DM) are common and are associated with an increased risk of complications and mortality. The severity of hyperglycaemia determines the rate of complications in patients treated in the emergency department (ED). Our aim was to examine whether determination of the capillary haemoglobin A1c (HbA1c) is a reliable method for detecting unknown diabetes and poor glycaemic control in the ED. A prospective observational study was conducted in adult (>18 years) patients treated in a single-centre ED. We compared the results of HbA1c levels measured by Bio-Rad in2it point-of-care device on a capillary blood sample and by the hospital laboratory. A total of 187 ED patients with an average age of 57.1 ± 19.2 years were studied. The mean HbA1c value was 5.78 ± 1.26 % by capillary POC testing and 6.10 ± 1.12 % by the hospital laboratory (correlation = 0.712, P < 0.001). A total of 17.1 % of cases had a prior diagnosis of DM. The diagnosis of DM (plasma glucose > 126 mg/dL and/or HbA1c > 6.5 %) was made in ten (5.4 %) additional cases (prior undiagnosed DM) for a total prior DM prevalence of 22.5 % (95 % CI 16.4-28.5 %). Capillary HbA1c detected 11 additional cases of unknown DM (5.9 %). A capillary HbA1c value greater than 6 % has a sensitivity of 85.7 % and specificity of 85.3 % for the screening of DM. Determination of the capillary HbA1c in the ED is a reliable, fast, and simple system for the screening of unknown or uncontrolled DM.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 56 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 26 46%
Student > Ph. D. Student 4 7%
Professor > Associate Professor 4 7%
Student > Postgraduate 3 5%
Researcher 3 5%
Other 9 16%
Unknown 7 13%
Readers by discipline Count As %
Medicine and Dentistry 35 63%
Nursing and Health Professions 4 7%
Biochemistry, Genetics and Molecular Biology 2 4%
Computer Science 2 4%
Agricultural and Biological Sciences 2 4%
Other 3 5%
Unknown 8 14%