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Amyloid-like aggregates of neuronal tau induced by formaldehyde promote apoptosis of neuronal cells

Overview of attention for article published in BMC Neuroscience, January 2007
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Title
Amyloid-like aggregates of neuronal tau induced by formaldehyde promote apoptosis of neuronal cells
Published in
BMC Neuroscience, January 2007
DOI 10.1186/1471-2202-8-9
Pubmed ID
Authors

Chun Lai Nie, Xing Sheng Wang, Ying Liu, Sarah Perrett, Rong Qiao He

Abstract

The microtubule associated protein tau is the principle component of neurofibrillar tangles, which are a characteristic marker in the pathology of Alzheimer's disease; similar lesions are also observed after chronic alcohol abuse. Formaldehyde is a common environmental contaminant and also a metabolite of methanol. Although many studies have been done on methanol and formaldehyde intoxication, none of these address the contribution of protein misfolding to the pathological mechanism, in particular the effect of formaldehyde on protein conformation and polymerization.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Netherlands 1 2%
Australia 1 2%
Unknown 55 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 29%
Researcher 12 21%
Student > Bachelor 7 12%
Student > Doctoral Student 4 7%
Student > Master 4 7%
Other 2 3%
Unknown 12 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 24%
Biochemistry, Genetics and Molecular Biology 9 16%
Medicine and Dentistry 8 14%
Neuroscience 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 4 7%
Other 5 9%
Unknown 13 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2012.
All research outputs
#12,736,376
of 22,664,267 outputs
Outputs from BMC Neuroscience
#502
of 1,240 outputs
Outputs of similar age
#132,507
of 160,838 outputs
Outputs of similar age from BMC Neuroscience
#2
of 3 outputs
Altmetric has tracked 22,664,267 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,240 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 160,838 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.