Title |
Gut-central nervous system axis is a target for nutritional therapies
|
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Published in |
Nutrition Journal, April 2012
|
DOI | 10.1186/1475-2891-11-22 |
Pubmed ID | |
Authors |
Gustavo D Pimentel, Thayana O Micheletti, Fernanda Pace, José C Rosa, Ronaldo VT Santos, Fabio S Lira |
Abstract |
Historically, in the 1950s, the chemist Linus Pauling established a relationship between decreased longevity and obesity. At this time, with the advent of studies involving the mechanisms that modulate appetite control, some researchers observed that the hypothalamus is the "appetite centre" and that peripheral tissues have important roles in the modulation of gut inflammatory processes and levels of hormones that control food intake. Likewise, the advances of physiological and molecular mechanisms for patients with obesity, type 2 diabetes mellitus, inflammatory bowel diseases, bariatric surgery and anorexia-associated diseases has been greatly appreciated by nutritionists. Therefore, this review highlights the relationship between the gut-central nervous system axis and targets for nutritional therapies. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 17% |
United Kingdom | 1 | 8% |
Ireland | 1 | 8% |
Canada | 1 | 8% |
Brazil | 1 | 8% |
Australia | 1 | 8% |
Unknown | 5 | 42% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 10 | 83% |
Science communicators (journalists, bloggers, editors) | 1 | 8% |
Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 2% |
United States | 2 | 1% |
Ethiopia | 1 | <1% |
Ireland | 1 | <1% |
Australia | 1 | <1% |
Brazil | 1 | <1% |
Indonesia | 1 | <1% |
Canada | 1 | <1% |
Norway | 1 | <1% |
Other | 2 | 1% |
Unknown | 179 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 32 | 17% |
Student > Master | 30 | 16% |
Student > Ph. D. Student | 25 | 13% |
Researcher | 23 | 12% |
Student > Postgraduate | 18 | 9% |
Other | 42 | 22% |
Unknown | 23 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 64 | 33% |
Agricultural and Biological Sciences | 45 | 23% |
Nursing and Health Professions | 11 | 6% |
Immunology and Microbiology | 9 | 5% |
Biochemistry, Genetics and Molecular Biology | 8 | 4% |
Other | 22 | 11% |
Unknown | 34 | 18% |