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The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile

Overview of attention for article published in Nutrition Journal, September 2008
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)

Mentioned by

news
6 news outlets
twitter
4 tweeters
facebook
4 Facebook pages
googleplus
1 Google+ user

Citations

dimensions_citation
106 Dimensions

Readers on

mendeley
217 Mendeley
citeulike
1 CiteULike
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Title
The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile
Published in
Nutrition Journal, September 2008
DOI 10.1186/1475-2891-7-29
Pubmed ID
Authors

Daria Brambilla, Cesare Mancuso, Mariagrazia Rita Scuderi, Paolo Bosco, Giuseppina Cantarella, Laurence Lempereur, Giulia Di Benedetto, Salvatore Pezzino, Renato Bernardini

Abstract

This review will discuss some issues related to the risk/benefit profile of the use of dietary antioxidants. Thus, recent progress regarding the potential benefit of dietary antioxidants in the treatment of chronic diseases with a special focus on immune system and neurodegenerative disorders will be discussed here. It is well established that reactive oxygen species (ROS) play an important role in the etiology of numerous diseases, such as atherosclerosis, diabetes and cancer. Among the physiological defense system of the cell, the relevance of antioxidant molecules, such as glutathione and vitamins is quite well established. Recently, the interest of researchers has, for example, been conveyed on antioxidant enzyme systems, such as the heme oxygenase/biliverdin reductase system, which appears modulated by dietary antioxidant molecules, including polyphenols and beta-carotene. These systems possibly counteract oxidative damage very efficiently and finally modulate the activity of oxidative phenomena occurring, for instance, during pathophysiological processes. Although evidence shows that antioxidant treatment results in cytoprotection, the potential clinical benefit deriving from both nutritional and supplemental antioxidants is still under wide debate. In this line, the inappropriate assumption of some lipophylic vitamins has been associated with increased incidence of cancer rather than with beneficial effects.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 217 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 4 2%
India 2 <1%
Turkey 1 <1%
China 1 <1%
Thailand 1 <1%
United States 1 <1%
Unknown 207 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 47 22%
Researcher 30 14%
Student > Ph. D. Student 27 12%
Student > Master 25 12%
Student > Doctoral Student 15 7%
Other 44 20%
Unknown 29 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 71 33%
Medicine and Dentistry 34 16%
Biochemistry, Genetics and Molecular Biology 19 9%
Pharmacology, Toxicology and Pharmaceutical Science 13 6%
Immunology and Microbiology 8 4%
Other 27 12%
Unknown 45 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 52. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 November 2020.
All research outputs
#635,707
of 21,578,868 outputs
Outputs from Nutrition Journal
#195
of 1,396 outputs
Outputs of similar age
#3,084
of 142,418 outputs
Outputs of similar age from Nutrition Journal
#1
of 1 outputs
Altmetric has tracked 21,578,868 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,396 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 33.8. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 142,418 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them