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Genetic deletion of dectin-1 does not affect the course of murine experimental colitis

Overview of attention for article published in BMC Gastroenterology, April 2012
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Title
Genetic deletion of dectin-1 does not affect the course of murine experimental colitis
Published in
BMC Gastroenterology, April 2012
DOI 10.1186/1471-230x-12-33
Pubmed ID
Authors

Sigrid EM Heinsbroek, Anneke Oei, Joris JTH Roelofs, Shobhit Dhawan, Anje te Velde, Siamon Gordon, Wouter J de Jonge

Abstract

It is believed that inflammatory bowel diseases (IBD) result from an imbalance in the intestinal immune response towards the luminal microbiome. Dectin-1 is a widely expressed pattern recognition receptor that recognizes fungi and upon recognition it mediates cytokine responses and skewing of the adaptive immune system. Hence, dectin-1 may be involved in the pathogenesis of IBD.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ireland 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 22%
Student > Master 6 13%
Student > Ph. D. Student 5 11%
Student > Postgraduate 5 11%
Professor > Associate Professor 4 9%
Other 7 16%
Unknown 8 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 27%
Medicine and Dentistry 11 24%
Immunology and Microbiology 5 11%
Biochemistry, Genetics and Molecular Biology 2 4%
Psychology 1 2%
Other 3 7%
Unknown 11 24%