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Estimating the effect of SNP genotype on quantitative traits from pooled DNA samples

Overview of attention for article published in Genetics Selection Evolution, April 2012
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Title
Estimating the effect of SNP genotype on quantitative traits from pooled DNA samples
Published in
Genetics Selection Evolution, April 2012
DOI 10.1186/1297-9686-44-12
Pubmed ID
Authors

John M Henshall, Rachel J Hawken, Sonja Dominik, William Barendse

Abstract

Studies to detect associations between DNA markers and traits of interest in humans and livestock benefit from increasing the number of individuals genotyped. Performing association studies on pooled DNA samples can provide greater power for a given cost. For quantitative traits, the effect of an SNP is measured in the units of the trait and here we propose and demonstrate a method to estimate SNP effects on quantitative traits from pooled DNA data.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
India 1 2%
Unknown 47 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 35%
Student > Ph. D. Student 12 24%
Student > Master 7 14%
Student > Postgraduate 3 6%
Professor 3 6%
Other 5 10%
Unknown 2 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 69%
Medicine and Dentistry 5 10%
Biochemistry, Genetics and Molecular Biology 3 6%
Computer Science 2 4%
Business, Management and Accounting 1 2%
Other 1 2%
Unknown 3 6%