Title |
Human-animal chimeras for vaccine development: an endangered species or opportunity for the developing world?
|
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Published in |
BMC Public Health, May 2010
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DOI | 10.1186/1472-698x-10-8 |
Pubmed ID | |
Authors |
Anant Bhan, Peter A Singer, Abdallah S Daar |
Abstract |
In recent years, the field of vaccines for diseases such as Human Immunodeficiency Virus (HIV) which take a heavy toll in developing countries has faced major failures. This has led to a call for more basic science research, and development as well as evaluation of new vaccine candidates. Human-animal chimeras, developed with a 'humanized' immune system could be useful to study infectious diseases, including many neglected diseases. These would also serve as an important tool for the efficient testing of new vaccine candidates to streamline promising candidates for further trials in humans. However, developing human-animal chimeras has proved to be controversial. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 25% |
Switzerland | 1 | 8% |
Germany | 1 | 8% |
Unknown | 7 | 58% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 75% |
Science communicators (journalists, bloggers, editors) | 1 | 8% |
Scientists | 1 | 8% |
Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Brazil | 2 | 2% |
Germany | 1 | 1% |
United Kingdom | 1 | 1% |
Unknown | 94 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 19 | 19% |
Researcher | 16 | 16% |
Student > Bachelor | 13 | 13% |
Student > Ph. D. Student | 7 | 7% |
Student > Postgraduate | 6 | 6% |
Other | 18 | 18% |
Unknown | 21 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 20 | 20% |
Agricultural and Biological Sciences | 19 | 19% |
Biochemistry, Genetics and Molecular Biology | 6 | 6% |
Nursing and Health Professions | 6 | 6% |
Social Sciences | 6 | 6% |
Other | 23 | 23% |
Unknown | 20 | 20% |