Title |
Hypochlorite-induced oxidative stress elevates the capability of HDL in promoting breast cancer metastasis
|
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Published in |
Journal of Translational Medicine, March 2012
|
DOI | 10.1186/1479-5876-10-65 |
Pubmed ID | |
Authors |
Bing Pan, Hui Ren, Xiaofeng Lv, Yangyu Zhao, Baoqi Yu, Yubin He, Yijing Ma, Chenguang Niu, Jinge Kong, Fangzhu Yu, Wen-bing Sun, Youyi Zhang, Belinda Willard, Lemin Zheng |
Abstract |
Previous studies suggest that oxidative stress plays an important role in the development of breast cancer. There is a significant inverse relationship between HDL and the risk and mortality of breast cancer. However, it is well known that under conditions of oxidative stress, such as breast cancer, HDL can be oxidatively modifiedand these modifications may have an effect on the functions of HDL. The purpose of this study is to determine the different effects of normal and oxidized (caused by hypochlorite-induced oxidative stress) HDL on breast cancer cell metastasis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Sri Lanka | 1 | 3% |
Unknown | 39 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 20% |
Researcher | 6 | 15% |
Student > Master | 5 | 13% |
Other | 4 | 10% |
Student > Bachelor | 4 | 10% |
Other | 5 | 13% |
Unknown | 8 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 25% |
Agricultural and Biological Sciences | 7 | 18% |
Biochemistry, Genetics and Molecular Biology | 5 | 13% |
Chemistry | 5 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Other | 2 | 5% |
Unknown | 9 | 23% |