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Downregulation of both gene expression and activity of Hsp27 improved maturation of mouse oocyte in vitro

Overview of attention for article published in Reproductive Biology and Endocrinology, May 2010
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Title
Downregulation of both gene expression and activity of Hsp27 improved maturation of mouse oocyte in vitro
Published in
Reproductive Biology and Endocrinology, May 2010
DOI 10.1186/1477-7827-8-47
Pubmed ID
Authors

Jin-Juan Liu, Xiang Ma, Ling-Bo Cai, Yu-Gui Cui, Jia-Yin Liu

Abstract

Heat shock protein 27 (Hsp27), a member of the small heat shock protein family, is an apoptosis regulator. Our previous proteomic study showed that Hsp27 mainly expressed in human oocyte, and that Hsp27 expression was downregulated in the ovaries derived from women with the polycystic ovary syndrome (PCOS), a well known endocrinal disorder with abnormal apoptotic activity and folliculogenesis. However, the exact effects of Hsp27 downregulation on oocyte development have not yet been clarified.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 4%
Unknown 27 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 32%
Student > Ph. D. Student 6 21%
Student > Doctoral Student 4 14%
Professor > Associate Professor 2 7%
Other 1 4%
Other 4 14%
Unknown 2 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 43%
Biochemistry, Genetics and Molecular Biology 5 18%
Medicine and Dentistry 3 11%
Unspecified 1 4%
Veterinary Science and Veterinary Medicine 1 4%
Other 2 7%
Unknown 4 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2012.
All research outputs
#15,242,847
of 22,664,267 outputs
Outputs from Reproductive Biology and Endocrinology
#525
of 965 outputs
Outputs of similar age
#77,332
of 95,115 outputs
Outputs of similar age from Reproductive Biology and Endocrinology
#2
of 3 outputs
Altmetric has tracked 22,664,267 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 965 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.9. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,115 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.