Title |
Treatment of endometriosis in different ethnic populations: a meta-analysis of two clinical trials
|
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Published in |
BMC Women's Health, April 2012
|
DOI | 10.1186/1472-6874-12-9 |
Pubmed ID | |
Authors |
Christoph Gerlinger, Thomas Faustmann, Jeffrey J Hassall, Christian Seitz |
Abstract |
Approaches to the treatment of endometriosis vary worldwide, but studies comparing endometriosis medications in different ethnic groups are rare. A systematic literature search identified two studies directly comparing dienogest (DNG) versus gonadotropin-releasing hormone (GnRH) analogues in European and Japanese populations. Meta-analysis of visual analogue scale scores revealed no heterogeneity in response between the trials, indicating equivalent efficacy of DNG and GnRH analogues for endometriosis-related pain across populations. DNG was significantly superior to GnRH analogues for bone mineral density change in both trials, but significant heterogeneity between the studies may indicate ethnic differences in physiology. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 33% |
Ireland | 1 | 17% |
Australia | 1 | 17% |
Unknown | 2 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 83% |
Scientists | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Peru | 1 | 2% |
Unknown | 65 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 12% |
Student > Postgraduate | 7 | 11% |
Student > Bachelor | 7 | 11% |
Other | 5 | 8% |
Student > Master | 5 | 8% |
Other | 11 | 17% |
Unknown | 23 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 42% |
Agricultural and Biological Sciences | 4 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Nursing and Health Professions | 1 | 2% |
Other | 2 | 3% |
Unknown | 27 | 41% |