Title |
Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission
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Published in |
Malaria Journal, April 2012
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DOI | 10.1186/1475-2875-11-118 |
Pubmed ID | |
Authors |
Bernadette J Huho, Gerard F Killeen, Heather M Ferguson, Adriana Tami, Christian Lengeler, J Derek Charlwood, Aniset Kihonda, Japhet Kihonda, S Patrick Kachur, Thomas A Smith, Salim MK Abdulla |
Abstract |
Artemisinin-based combination therapy (ACT) for treating malaria has activity against immature gametocytes. In theory, this property may complement the effect of terminating otherwise lengthy malaria infections and reducing the parasite reservoir in the human population that can infect vector mosquitoes. However, this has never been verified at a population level in a setting with intense transmission, where chronically infectious asymptomatic carriers are common and cured patients are rapidly and repeatedly re-infected. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 50% |
Hong Kong | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | <1% |
Tanzania, United Republic of | 1 | <1% |
Indonesia | 1 | <1% |
Switzerland | 1 | <1% |
Australia | 1 | <1% |
Vietnam | 1 | <1% |
Belgium | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 197 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 9% |
Student > Ph. D. Student | 15 | 7% |
Student > Master | 11 | 5% |
Other | 6 | 3% |
Student > Bachelor | 4 | 2% |
Other | 13 | 6% |
Unknown | 139 | 67% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 9% |
Agricultural and Biological Sciences | 11 | 5% |
Social Sciences | 6 | 3% |
Biochemistry, Genetics and Molecular Biology | 5 | 2% |
Computer Science | 3 | 1% |
Other | 21 | 10% |
Unknown | 141 | 68% |