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Effects of human and porcine bile on the proteome of Helicobacter hepaticus

Overview of attention for article published in Proteome Science, April 2012
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Title
Effects of human and porcine bile on the proteome of Helicobacter hepaticus
Published in
Proteome Science, April 2012
DOI 10.1186/1477-5956-10-27
Pubmed ID
Authors

Arinze S Okoli, Mark J Raftery, George L Mendz

Abstract

Helicobacter hepaticus colonizes the intestine and liver of mice causing hepatobiliary disorders such as hepatitis and hepatocellular carcinoma, and has also been associated with inflammatory bowel disease in children. In its habitat, H. hepaticus must encounter bile which has potent antibacterial properties. To elucidate virulence and host-specific adaptation mechanisms of H. hepaticus modulated by human or porcine bile, a proteomic study of its response to the two types of bile was performed employing two-dimensional gel electrophoresis (2-DE) and mass spectrometry.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 17%
Student > Bachelor 2 11%
Professor 2 11%
Student > Master 2 11%
Student > Ph. D. Student 1 6%
Other 2 11%
Unknown 6 33%
Readers by discipline Count As %
Medicine and Dentistry 4 22%
Agricultural and Biological Sciences 3 17%
Biochemistry, Genetics and Molecular Biology 2 11%
Environmental Science 1 6%
Psychology 1 6%
Other 1 6%
Unknown 6 33%