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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genetic characterization of TEM-type ESBL-associated antibacterial resistance in Enterobacteriaceae in a tertiary hospital in Ghana
|
|---|---|
| Published in |
Annals of Clinical Microbiology and Antimicrobials, May 2016
|
| DOI | 10.1186/s12941-016-0144-2 |
| Pubmed ID | |
| Authors |
Daniel Oduro-Mensah, Noah Obeng-Nkrumah, Evelyn Yayra Bonney, Ebenezer Oduro-Mensah, Kingsley Twum-Danso, Yaa Difie Osei, Sammy Tawiah Sackey |
| Abstract |
Antibiotic resistance due to the presence of extended-spectrum beta-lactamases (ESBLs) among Enterobacteriaceae is a worldwide problem. Data from Ghana regarding this resistance mechanism is limited. This study was designed to investigate the presence of TEM-type ESBL genes, their locations and their conjugabilities in clinical isolates of enterobacteria collected from the Korle-Bu Teaching Hospital in Ghana. Study isolates were characterized with respect to ESBL phenotype, TEM-type ESBL gene detection, location of the ESBL gene(s) and conjugability of the ESBL phenotype using nalidixic acid-resistant Escherichia coli K-12 as recipient. Phenotyping was by Kirby Bauer disk diffusion using cefpodoxime, ceftazidime, cefotaxime and their combinations with clavulanate. Gene detections were by PCR using blaTEM primers. Overall, 37.96 % of 137 clinical isolates showed ESBL phenotype. The ESBLs occurred mostly in Klebsiella spp. (42.3 %) and then Escherichia coli (34.6 %). The TEM gene was detected in 48.1 % of ESBL-positive isolates and was determined to be plasmid-borne in 24 of 25 blaTEM detections. Overall, 62.7 % of TEM-producing isolates transferred the ESBL phenotype by conjugation. The results highlight the presence of TEM-type ESBLs in the Korle-Bu Teaching Hospital and show considerable risk of environmental contamination through the urine of infected persons. An inhibition zone chart was generated which indicates the possible presence of complex beta-lactamase types. The data points to the fact that the ESBL-producing bacteria may disseminate this resistance mechanism via conjugation. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Malaysia | 1 | 13% |
| United Kingdom | 1 | 13% |
| Australia | 1 | 13% |
| Venezuela, Bolivarian Republic of | 1 | 13% |
| Unknown | 4 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 50% |
| Practitioners (doctors, other healthcare professionals) | 2 | 25% |
| Scientists | 1 | 13% |
| Science communicators (journalists, bloggers, editors) | 1 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | <1% |
| Unknown | 136 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 20 | 15% |
| Student > Bachelor | 20 | 15% |
| Student > Ph. D. Student | 12 | 9% |
| Student > Postgraduate | 9 | 7% |
| Student > Doctoral Student | 8 | 6% |
| Other | 22 | 16% |
| Unknown | 46 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 26 | 19% |
| Medicine and Dentistry | 17 | 12% |
| Agricultural and Biological Sciences | 15 | 11% |
| Biochemistry, Genetics and Molecular Biology | 12 | 9% |
| Veterinary Science and Veterinary Medicine | 5 | 4% |
| Other | 13 | 9% |
| Unknown | 49 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2023.
All research outputs
#7,104,583
of 23,230,825 outputs
Outputs from Annals of Clinical Microbiology and Antimicrobials
#145
of 618 outputs
Outputs of similar age
#99,284
of 299,739 outputs
Outputs of similar age from Annals of Clinical Microbiology and Antimicrobials
#8
of 17 outputs
Altmetric has tracked 23,230,825 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 618 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,739 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.