Title |
A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response
|
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Published in |
Genome Biology, April 2012
|
DOI | 10.1186/gb-2012-13-4-r32 |
Pubmed ID | |
Authors |
Scott Schwartz, Iddo Friedberg, Ivan V Ivanov, Laurie A Davidson, Jennifer S Goldsby, David B Dahl, Damir Herman, Mei Wang, Sharon M Donovan, Robert S Chapkin |
Abstract |
Gut microbiota and the host exist in a mutualistic relationship, with the functional composition of the microbiota strongly affecting the health and well-being of the host. Thus, it is important to develop a synthetic approach to study the host transcriptome and the microbiome simultaneously. Early microbial colonization in infants is critically important for directing neonatal intestinal and immune development, and is especially attractive for studying the development of human-commensal interactions. Here we report the results from a simultaneous study of the gut microbiome and host epithelial transcriptome of three-month-old exclusively breast- and formula-fed infants. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 14 | 35% |
Spain | 3 | 8% |
United Kingdom | 3 | 8% |
Chile | 2 | 5% |
Australia | 1 | 3% |
Canada | 1 | 3% |
Germany | 1 | 3% |
India | 1 | 3% |
Unknown | 14 | 35% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 26 | 65% |
Scientists | 7 | 18% |
Practitioners (doctors, other healthcare professionals) | 6 | 15% |
Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 13 | 2% |
United Kingdom | 10 | 2% |
Italy | 4 | <1% |
Ireland | 2 | <1% |
Sweden | 2 | <1% |
Israel | 2 | <1% |
Brazil | 1 | <1% |
Vietnam | 1 | <1% |
Finland | 1 | <1% |
Other | 9 | 1% |
Unknown | 559 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 127 | 21% |
Researcher | 122 | 20% |
Student > Master | 77 | 13% |
Student > Bachelor | 59 | 10% |
Student > Doctoral Student | 31 | 5% |
Other | 106 | 18% |
Unknown | 82 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 242 | 40% |
Medicine and Dentistry | 77 | 13% |
Biochemistry, Genetics and Molecular Biology | 53 | 9% |
Immunology and Microbiology | 33 | 5% |
Nursing and Health Professions | 18 | 3% |
Other | 83 | 14% |
Unknown | 98 | 16% |