Title |
Experimental Actinobacillus pleuropneumoniaechallenge in swine: Comparison of computed tomographic and radiographic findings during disease
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Published in |
BMC Veterinary Research, April 2012
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DOI | 10.1186/1746-6148-8-47 |
Pubmed ID | |
Authors |
Carsten Brauer, Isabel Hennig-Pauka, Doris Hoeltig, Falk FR Buettner, Martin Beyerbach, Hagen Gasse, Gerald-F Gerlach, Karl-H Waldmann |
Abstract |
In pigs, diseases of the respiratory tract like pleuropneumonia due to Actinobacillus pleuropneumoniae (App) infection have led to high economic losses for decades. Further research on disease pathogenesis, pathogen-host-interactions and new prophylactic and therapeutic approaches are needed. In most studies, a large number of experimental animals are required to assess lung alterations at different stages of the disease. In order to reduce the required number of animals but nevertheless gather information on the nature and extent of lung alterations in living pigs, a computed tomographic scoring system for quantifying gross pathological findings was developed. In this study, five healthy pigs served as control animals while 24 pigs were infected with App, the causative agent of pleuropneumonia in pigs, in an established model for respiratory tract disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 7 | 28% |
Researcher | 4 | 16% |
Student > Master | 3 | 12% |
Professor | 3 | 12% |
Student > Doctoral Student | 2 | 8% |
Other | 2 | 8% |
Unknown | 4 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 28% |
Veterinary Science and Veterinary Medicine | 4 | 16% |
Medicine and Dentistry | 4 | 16% |
Biochemistry, Genetics and Molecular Biology | 3 | 12% |
Business, Management and Accounting | 1 | 4% |
Other | 2 | 8% |
Unknown | 4 | 16% |