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Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage

Overview of attention for article published in Journal of Translational Medicine, April 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

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5 X users
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5 patents

Citations

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106 Dimensions

Readers on

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77 Mendeley
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Title
Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage
Published in
Journal of Translational Medicine, April 2012
DOI 10.1186/1479-5876-10-80
Pubmed ID
Authors

Ryosuke Echigo, Nobuyuki Shimohata, Kensuke Karatsu, Fumiko Yano, Yuko Kayasuga-Kariya, Ayano Fujisawa, Takayo Ohto, Yoshihiro Kita, Motonao Nakamura, Shigeki Suzuki, Manabu Mochizuki, Takao Shimizu, Ung-il Chung, Nobuo Sasaki

Abstract

Subarachnoid hemorrhage (SAH) frequently results in several complications, including cerebral vasospasm, associated with high mortality. Although cerebral vasospasm is a major cause of brain damages after SAH, other factors such as inflammatory responses and oxidative stress also contribute to high mortality after SAH. Trehalose is a non-reducing disaccharide in which two glucose units are linked by α,α-1,1-glycosidic bond, and has been shown to induce tolerance to a variety of stressors in numerous organisms. In the present study, we investigated the effect of trehalose on cerebral vasospasm, inflammatory responses, and oxidative stress induced by blood in vitro and in vivo.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Unknown 75 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 23%
Student > Doctoral Student 9 12%
Student > Master 8 10%
Student > Ph. D. Student 5 6%
Student > Bachelor 3 4%
Other 12 16%
Unknown 22 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 26%
Biochemistry, Genetics and Molecular Biology 12 16%
Medicine and Dentistry 10 13%
Chemistry 2 3%
Veterinary Science and Veterinary Medicine 2 3%
Other 7 9%
Unknown 24 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2024.
All research outputs
#2,520,526
of 25,641,627 outputs
Outputs from Journal of Translational Medicine
#444
of 4,692 outputs
Outputs of similar age
#15,062
of 175,493 outputs
Outputs of similar age from Journal of Translational Medicine
#4
of 63 outputs
Altmetric has tracked 25,641,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,692 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.8. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 175,493 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.