Title |
Systemic therapy in the management of metastatic or advanced salivary gland cancers
|
---|---|
Published in |
Head & Neck Oncology, May 2012
|
DOI | 10.1186/1758-3284-4-19 |
Pubmed ID | |
Authors |
Aymen Lagha, Nesrine Chraiet, Mouna Ayadi, Sarra Krimi, Bassem Allani, Hela Rifi, Henda Raies, Amel Mezlini |
Abstract |
Salivary gland cancers are very rare tumors. They are characterized by a histologic heterogeneity and a poor outcome. According to this rarity, few prospective data are available to date. No standard recommendations could be held for the use of systemic therapy in these tumors. Several case reports and small studies have investigated the contribution of different agents of chemotherapy. With the extension of molecular biology approach in oncology several signaling pathways have been discovered in different cancers including salivary gland cancers; thus a number of targeted therapies have been investigated. This paper reviewed exhaustively the studies investigating the role of systemic therapies (chemotherapy, targeted therapy, hormone therapy) in salivary gland cancers. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 3% |
Spain | 1 | 3% |
Unknown | 33 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 6 | 17% |
Student > Doctoral Student | 6 | 17% |
Lecturer | 3 | 9% |
Student > Bachelor | 3 | 9% |
Researcher | 3 | 9% |
Other | 7 | 20% |
Unknown | 7 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 51% |
Biochemistry, Genetics and Molecular Biology | 4 | 11% |
Agricultural and Biological Sciences | 1 | 3% |
Physics and Astronomy | 1 | 3% |
Immunology and Microbiology | 1 | 3% |
Other | 0 | 0% |
Unknown | 10 | 29% |