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Ultrahigh-dimensional variable selection method for whole-genome gene-gene interaction analysis

Overview of attention for article published in BMC Bioinformatics, May 2012
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Mentioned by

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3 X users

Citations

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34 Dimensions

Readers on

mendeley
67 Mendeley
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2 CiteULike
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Title
Ultrahigh-dimensional variable selection method for whole-genome gene-gene interaction analysis
Published in
BMC Bioinformatics, May 2012
DOI 10.1186/1471-2105-13-72
Pubmed ID
Authors

Masao Ueki, Gen Tamiya

Abstract

Genome-wide gene-gene interaction analysis using single nucleotide polymorphisms (SNPs) is an attractive way for identification of genetic components that confers susceptibility of human complex diseases. Individual hypothesis testing for SNP-SNP pairs as in common genome-wide association study (GWAS) however involves difficulty in setting overall p-value due to complicated correlation structure, namely, the multiple testing problem that causes unacceptable false negative results. A large number of SNP-SNP pairs than sample size, so-called the large p small n problem, precludes simultaneous analysis using multiple regression. The method that overcomes above issues is thus needed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
Malaysia 1 1%
Germany 1 1%
Belgium 1 1%
Unknown 63 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 30%
Researcher 14 21%
Student > Master 9 13%
Student > Bachelor 4 6%
Student > Postgraduate 4 6%
Other 11 16%
Unknown 5 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 19%
Computer Science 13 19%
Biochemistry, Genetics and Molecular Biology 8 12%
Mathematics 6 9%
Medicine and Dentistry 4 6%
Other 13 19%
Unknown 10 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2012.
All research outputs
#13,360,809
of 22,664,644 outputs
Outputs from BMC Bioinformatics
#4,186
of 7,247 outputs
Outputs of similar age
#91,029
of 163,491 outputs
Outputs of similar age from BMC Bioinformatics
#59
of 103 outputs
Altmetric has tracked 22,664,644 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,247 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,491 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 103 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.