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Pediatric spinal glioblastoma of the conus medullaris: a case report of long survival

Overview of attention for article published in Cancer Communications, May 2016
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Title
Pediatric spinal glioblastoma of the conus medullaris: a case report of long survival
Published in
Cancer Communications, May 2016
DOI 10.1186/s40880-016-0107-1
Pubmed ID
Authors

Antonella Cacchione, Angela Mastronuzzi, Maria Giuseppina Cefalo, Giovanna Stefania Colafati, Francesca Diomedi-Camassei, Michele Rizzi, Alessandro De Benedictis, Andrea Carai

Abstract

High-grade gliomas of the spinal cord represent a rare entity in children. Their biology, behavior, and controversial treatment options have been discussed in a few pediatric cases. These tumors are associated with severe disability and poor prognosis. We report a case of a 4-year-old child diagnosed with an isolated glioblastoma multiforme of the conus medullaris. The patient underwent subtotal surgical excision, followed by adjuvant radiotherapy and oral chemotherapy. He is alive with mild neurologic deficits at 52 months after diagnosis. We describe the peculiar characteristics of this rare condition in pediatric oncology. We also provide an overview of current multidisciplinary therapeutic approaches and prognostic factors for this disease.

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Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 25%
Student > Master 4 17%
Other 1 4%
Student > Doctoral Student 1 4%
Librarian 1 4%
Other 4 17%
Unknown 7 29%
Readers by discipline Count As %
Medicine and Dentistry 9 38%
Nursing and Health Professions 3 13%
Unspecified 1 4%
Agricultural and Biological Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 2 8%
Unknown 7 29%