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Modified-live PRRSV subtype 1 vaccine UNISTRAIN® PRRS provides a partial clinical and virological protection upon challenge with East European subtype 3 PRRSV strain Lena

Overview of attention for article published in Porcine Health Management, May 2016
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Title
Modified-live PRRSV subtype 1 vaccine UNISTRAIN® PRRS provides a partial clinical and virological protection upon challenge with East European subtype 3 PRRSV strain Lena
Published in
Porcine Health Management, May 2016
DOI 10.1186/s40813-016-0029-y
Pubmed ID
Authors

Caroline Bonckaert, Karen van der Meulen, Isaac Rodríguez-Ballarà, Rafael Pedrazuela Sanz, Mar Fenech Martinez, Hans J. Nauwynck

Abstract

Western European porcine reproductive and respiratory syndrome virus (PRRSV) strains cause limited and mild clinical signs whereas more virulent strains are circulating in Eastern Europe. The emergence of such highly virulent strains in Western Europe might result in severe clinical problems and a financial disaster. In this context, the efficacy of the commercial modified-live PRRSV subtype 1 vaccine UNISTRAIN(®) PRRS was tested upon challenge with the East European subtype 3 PRRSV strain Lena. The mean duration of fever was shortened and the number of fever days was significantly lower in vaccinated pigs than in control pigs. Moreover, a lower number of vaccinated animals showed fever, respiratory disorders and conjunctivitis. The mean virus titers in the nasal secretions post challenge (AUC) were significantly lower in the vaccinated group than in the control group. The duration of viremia was slightly shorter (not significantly different) in the vaccinated group as compared to the control group. Vaccination of pigs with the modified-live vaccine UNISTRAIN(®) PRRS provides a partial clinical and virological protection against the PRRSV subtype 3 strain Lena.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 19%
Student > Bachelor 3 14%
Student > Master 3 14%
Other 2 10%
Student > Ph. D. Student 2 10%
Other 3 14%
Unknown 4 19%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 6 29%
Agricultural and Biological Sciences 3 14%
Unspecified 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Nursing and Health Professions 1 5%
Other 3 14%
Unknown 6 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2019.
All research outputs
#17,802,399
of 22,869,263 outputs
Outputs from Porcine Health Management
#179
of 221 outputs
Outputs of similar age
#207,453
of 301,827 outputs
Outputs of similar age from Porcine Health Management
#3
of 4 outputs
Altmetric has tracked 22,869,263 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 221 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 301,827 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.