Title |
Untranslated regions of diverse plant viral RNAs vary greatly in translation enhancement efficiency
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Published in |
BMC Biotechnology, May 2012
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DOI | 10.1186/1472-6750-12-22 |
Pubmed ID | |
Authors |
Qiuling Fan, Krzysztof Treder, W Allen Miller |
Abstract |
Whole plants or plant cell cultures can serve as low cost bioreactors to produce massive amounts of a specific protein for pharmacological or industrial use. To maximize protein expression, translation of mRNA must be optimized. Many plant viral RNAs harbor extremely efficient translation enhancers. However, few of these different translation elements have been compared side-by-side. Thus, it is unclear which are the most efficient translation enhancers. Here, we compare the effects of untranslated regions (UTRs) containing translation elements from six plant viruses on translation in wheat germ extract and in monocotyledenous and dicotyledenous plant cells. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 2% |
Poland | 1 | 2% |
Unknown | 58 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 17 | 28% |
Researcher | 11 | 18% |
Student > Master | 8 | 13% |
Professor > Associate Professor | 3 | 5% |
Professor | 3 | 5% |
Other | 5 | 8% |
Unknown | 13 | 22% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 23 | 38% |
Biochemistry, Genetics and Molecular Biology | 15 | 25% |
Medicine and Dentistry | 2 | 3% |
Engineering | 2 | 3% |
Immunology and Microbiology | 1 | 2% |
Other | 2 | 3% |
Unknown | 15 | 25% |