Title |
DNA-testing for BRCA1/2 prior to genetic counselling in patients with breast cancer: design of an intervention study, DNA-direct
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Published in |
BMC Women's Health, May 2012
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DOI | 10.1186/1472-6874-12-12 |
Pubmed ID | |
Authors |
Aisha S Sie, Liesbeth Spruijt, Wendy AG van Zelst-Stams, Arjen R Mensenkamp, Marjolijn J Ligtenberg, Han G Brunner, Judith B Prins, Nicoline Hoogerbrugge |
Abstract |
Current practice for patients with breast cancer referred for genetic counseling, includes face-to-face consultations with a genetic counselor prior to and following DNA-testing. This is based on guidelines regarding Huntington's disease in anticipation of high psychosocial impact of DNA-testing for mutations in BRCA1/2 genes. The initial consultation covers generic information regarding hereditary breast cancer and the (im)possibilities of DNA-testing, prior to such testing. Patients with breast cancer may see this information as irrelevant or unnecessary because individual genetic advice depends on DNA-test results. Also, verbal information is not always remembered well by patients. A different format for this information prior to DNA-testing is possible: replacing initial face-to-face genetic counseling (DNA-intake procedure) by telephone, written and digital information sent to patients' homes (DNA-direct procedure). |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 50% |
United States | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 3% |
Brazil | 1 | 1% |
Unknown | 82 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 14% |
Student > Doctoral Student | 12 | 14% |
Student > Ph. D. Student | 11 | 13% |
Researcher | 8 | 9% |
Student > Bachelor | 8 | 9% |
Other | 18 | 21% |
Unknown | 17 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 20 | 23% |
Psychology | 12 | 14% |
Nursing and Health Professions | 9 | 10% |
Agricultural and Biological Sciences | 9 | 10% |
Social Sciences | 6 | 7% |
Other | 11 | 13% |
Unknown | 19 | 22% |