The Mount Sinai BioMe biobank does have a diverse representation of the population in NYC. This has led to discoveries of founder variants that are not commonly recognized in clinical practice despite their prevalence https://t.co/iOfDZSomLT
Exome sequencing reveals a high prevalence of BRCA1 and BRCA2 founder variants in a diverse population-based biobank. https://t.co/fBS2VqH24W
@EimearEKenny EK: citing https://t.co/j57YtBIi8Y The prevalence of these variants are different among communities that are usually put in the same "buckets". Also see this in PRSs. Showing that distribution different for some traits between Ashk. Jewish EU
Exome sequencing reveals a high prevalence of BRCA1 and BRCA2 founder variants in a diverse population-based biobank - https://t.co/iyn8f32reX