↓ Skip to main content

Dental noise exposed mice display depressive-like phenotypes

Overview of attention for article published in Molecular Brain, May 2016
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
11 Dimensions

Readers on

mendeley
40 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Dental noise exposed mice display depressive-like phenotypes
Published in
Molecular Brain, May 2016
DOI 10.1186/s13041-016-0229-z
Pubmed ID
Authors

Yujie Dong, Ying Zhou, Xixia Chu, Shiqing Chen, Lei Chen, Beimeng Yang, Xu Zhang, Lin Wang, Shuai Wang, Jingyu Lou, Qing Deng, Li Wang, Zheyi Cao, Jianan Wang, Jiaxin Xie, Tatiana Serdyuk, Shengtian Li, Lin He, Xiaoping Chen, Weidong Li

Abstract

Studies have indicated that depressive disorders are observed frequently in dentists. It's suggested that dentists encounter numerous sources of stress in their professional career. We noticed that the noises in dental environments are very unpleasant. The animal modeling studies suggested that stressful noise could produce depressive-like phenotypes in rodent animals. We hypothesize that the dental noise may be one of the primary stressors causing depressive disorders in dentists. We treated C57BL/6 mice with programmatically played wide-spectrum dental noise for 8 h/day at 75 ± 10 dB SPL level for 30 days, and then tested the behaviors. After exposure to dental noise, animals displayed the depressive-like phenotypes, accompanied by inhibition of neurogenesis in hippocampus. These deficits were ameliorated by orally administered with antidepressant fluoxetine. Our results suggested that dental noise could be one of the primary stressors for the pathogenesis of depressive disorders and the dental noise mouse model could be used in further depression studies.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 25%
Student > Master 7 18%
Other 2 5%
Researcher 2 5%
Student > Ph. D. Student 2 5%
Other 4 10%
Unknown 13 33%
Readers by discipline Count As %
Medicine and Dentistry 7 18%
Neuroscience 4 10%
Nursing and Health Professions 3 8%
Psychology 3 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 4 10%
Unknown 17 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2016.
All research outputs
#18,456,836
of 22,869,263 outputs
Outputs from Molecular Brain
#862
of 1,111 outputs
Outputs of similar age
#224,347
of 304,990 outputs
Outputs of similar age from Molecular Brain
#27
of 31 outputs
Altmetric has tracked 22,869,263 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,111 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 304,990 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.