Title |
Severe reaction in a child with asymptomatic codfish allergy: Food challenge reactivating recurrent pancreatitis
|
---|---|
Published in |
Italian Journal of Pediatrics, May 2012
|
DOI | 10.1186/1824-7288-38-16 |
Pubmed ID | |
Authors |
Katia Pellegrino, Leila Emma D’Urbano, Maria Cristina Artesani, Carla Riccardi, Sandro Mancini, Sergio Bella, Federico Alghisi, Giovanni Cavagni |
Abstract |
An 8-year-old child during the first year of life manifested severe atopic dermatitis and chronic diarrhea with mucorrhea and rectal bleeding; a fish-free diet was started based on weakly positive skin-prick tests to codfish extract. At the age of 4 years the child began to suffer of recurrent pancreatitis. When he came to our attention for the evaluation of his fish allergy, he was asymptomatic; a weak reactivity to codfish was observed (SPTs: cod, 4 mm, sIgE ImmunoCAP: cod, 1.30 kU/l). The food challenge test with cod was negative. When the child ate cod again, within 5 minutes, developed anaphylactic reaction and complained of abdominal pain compatible with pancreatitis (enzyme serum levels risen and parenchymal oedema at ultrasonography), that resolved within 7 days after specific therapy. This case raises two issues: the elimination diet in asymptomatic food allergy on the basis only of SPT and the ethicality of food challenge in gastrointestinal chronic disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 33 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 21% |
Student > Master | 5 | 15% |
Student > Postgraduate | 4 | 12% |
Student > Bachelor | 4 | 12% |
Student > Doctoral Student | 1 | 3% |
Other | 6 | 18% |
Unknown | 6 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 48% |
Nursing and Health Professions | 4 | 12% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Unspecified | 1 | 3% |
Immunology and Microbiology | 1 | 3% |
Other | 3 | 9% |
Unknown | 6 | 18% |